Criteria for AAT deficiency testing-adapted from American Thoracic Society/Europien Respiratory Society Statement: Standards for diagnosis and management of AAT deficiency:

COPD (all subjects)
Early onset of pulmonary emphysema
Liver disease of unknown cause
Asthma whose spirometry fails to return to normal with therapy
Family members of known AAT-deficient patients
Dyspnea and cough occurring in multiple family members
Adults with bronchiectasis without event etiology
Unexplained panniculitis and anti-proteinase-3 vasculitis

AlphaTest® Kit is a safe and reliable test kit to assist in the diagnosis of alpha1-antitrypsin deficiency.